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# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Sat Jul 23 07:49:37 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/molybdopterin.html
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#====================================
# Aligned_structures: 4
# 1: 1aa6.pdb
# 2: 1cxsa.pdb
# 3: 1dmr.pdb
# 4: 1tmo.pdb
#
# Length: 895
# Identity: 79/895 ( 8.8%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 307/895 ( 34.3%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 301/895 ( 33.6%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1aa6.pdb 1 -----MKKVVTVCPYCAS-GCKINLVVDNGKIVRAEAAQGKTNQGTLC--LKGYYGWDFI 52
1cxsa.pdb 1 EGLA-NGEVMSGC-----HWGVFKARVENGRAVAFEPWD--KDPA---PSHQLPGVLDSI 49
1dmr.pdb 1 --LA-NGTVMSGS-----HWGVFTATVENGRATAFTPWE--KDPH---PSPMLAGVLDSI 47
1tmo.pdb 1 ---NEDEWLTTGS-----HFGAFKMKRKNGVIAEVKPFD--LDKY---PTDMINGIRGMV 47
v g g f v NG p d g d i
1aa6.pdb 53 NDTQILT-PRLKTPMIRRQ-------------RGGKLEPVSWDEALNYVAERLSAIKEKY 98
1cxsa.pdb 50 YS-----PTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVTWDEALDLVARELKRVQESY 104
1dmr.pdb 48 YS-----PTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETY 102
1tmo.pdb 48 YN-----PSRVRYPMVRLDFLLKGHKSNTHQRGDFRFVRVTWDKALTLFKHSLDEVQTQY 102
y R kyPMvRr g g fvrV WD AL lva l v e Y
1aa6.pdb 99 GPDAIQTT-GSSRGTGN-----ETNYVMQKFARAVIGTN-NVDCCARVHGPSVAGLHQSV 151
1cxsa.pdb 105 GPTGTFGGSYGWKS---PGRLHNCQVLMRRALNLAGGFVNSSGDY--STAAAQIIMPHVM 159
1dmr.pdb 103 GPEGVFGGSYGWKS---PGRLHNCTTLLRRMLTLAGGYVNGAGDY--STGAAQVIMPHVV 157
1tmo.pdb 103 GPSGLHAGQTGWRA---TGQLHSSTSHMQRAVGMHGNYVKKIGDY--STGAGQTILPYVL 157
GP g g gw m r gg v gdy stga q i p v
1aa6.pdb 152 GNGAM---SNAINEID-NTDLVFVFGYNPADSH-----------PIVANHVINAKRNG-A 195
1cxsa.pdb 160 GTLEVYEQQTAWPVVVENTDLMVFWAADPMKTNEIGWVIPDHGAYAGMK---ALKEKG-T 215
1dmr.pdb 158 GTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLE---ALKAKG-T 213
1tmo.pdb 158 GSTEVYAQGTSWPLILEHSDTIVLWSNDPYKNLQVGWNAETHESFAYLAQLKEKVKQGKI 217
G ev tawp ntd v w dP k k G
1aa6.pdb 196 KIIVCDPRKIETARIAD-MHIALKNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEY 254
1cxsa.pdb 216 RVICINPVRTETADYFGADVVSPRPQTDVALMLGMAHTLYSEDLHDKDFLENCTTGFDLF 275
1dmr.pdb 214 KVIVIDPVRTKTVEFFGAEHITPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKF 273
1tmo.pdb 218 RVISIDPVVTKTQAYLGCEQLYVNPQTDVTLMLAIAHEMISKKLYDDKFIQGYSLGFEEF 277
vI idPv t T g pqtdvalml maH e LyDk F t GF f
1aa6.pdb 255 RKIVE------GYTPESVEDITGVSASEIRQAARMYAQAKSAAILWGMGVTQFYQGVETV 308
1cxsa.pdb 276 AAYLTGESDGTPKTAEWAAEICGLPAEQIRELARSFVA-GRTMLAAGWSIQRMHHGEQAH 334
1dmr.pdb 274 LPYLDGETDSTPKTAEWAEGISGVPAETIKELARLFES-KRTMLAAGWSMQRMHHGEQAH 332
1tmo.pdb 278 VPYVMGTKDGVAKTPEWAAPICGVEAHVIRDLAKTLVK-GRTQFMMGWCIQRQQHGEQPY 336
y kT Ewa I Gv A Ir lAr rt Gw qr hGeq
1aa6.pdb 309 RSLTSLAMLTGNLGKPHAGVNPVR-GQNNVQGAC---------------DMGA---LPDT 349
1cxsa.pdb 335 WMLVTLASMIGQIGLPGGGFGLS-YH--------YSNGGSPTSDGPALGGISDGGW---- 381
1dmr.pdb 333 WMLVTLASMLGQIGLPGGGFGLS-YH--------YSGGGTPSTSGPALAGITD---G--- 377
1tmo.pdb 337 WMAAVLATMIGQIGLPGGGISYG-HH--------YSSIGVPSSGAAAPGAFPR---NLD- 383
wml LA m GqiGlPggG h
1aa6.pdb 350 Y-PGYQYVKDPANREKFAKAWGVE-SLPAHT--GYRISELPHRAAHG------------- 392
1cxsa.pdb 382 -------------------------------ATSIPCARVVDMLLNPGGEFQFNGATATY 410
1dmr.pdb 378 -GAATK---GP---------EWLAASG----ASVIPVARVVDMLENPGAEFDFNGTRSKF 420
1tmo.pdb 384 --ENQKPLFDS---------SDFK-GA----SSTIPVARWIDAILEPGKTIDANGSKVVY 427
ip ar d p
1aa6.pdb 393 -EVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGEHE 451
1cxsa.pdb 411 PDVKLAYWAGGNPFAHHQDRNRMLKAWEKLETFIVQDFQWTATARHADIVLPATTSYERN 470
1dmr.pdb 421 PDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFVVHDFQWTPTARHADIVLPATTSYERN 480
1tmo.pdb 428 PDIKMMIFSGNNPWNHHQDRNRMKQAFHKLECVVTVDVNWTATCRFSDIVLPACTTYERN 487
dvk ay G nP hhqdrnrm kA ekLE v D wT Tar aDivLPatt yErn
1aa6.pdb 452 GVFTAA--DR-GFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHY------NNTQEIWD 502
1cxsa.pdb 471 DIESVGDYSNRAILAMKKVVDPLYEARSDYDIFAALAERLGKG---AEFTEGRDEMGWIS 527
1dmr.pdb 481 DIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKG---AEFTEGKDEMGWIK 537
1tmo.pdb 488 DIDVYGAYANRGILAMQKMVEPLFDSLSDFEIFTRFAAVLGKE---KEYTRNMGEMEWLE 544
di g n gilam K VePl sD If A rlGk em w
1aa6.pdb 503 ELRHLC-PDFYG-----ATYEKMGEL-GFIQWPCRDTSDADQ--GTSYLFK--------E 545
1cxsa.pdb 528 SFYEAAVKQAEFKNVAMPSFEDFW-SEGIVEF-------PITEGANFVRYADFREDPLFN 579
1dmr.pdb 538 SFYDDAAKQGKAAGVQMPAFDAFW-AEGIVEF-------PVTDGADFVRYASFREDPLLN 589
1tmo.pdb 545 TLYNECKAANAG-KFEMPDFATFW-KQGYVHF-------GDG--EVWTRHADFRNDPEIN 593
y p f fw G v f r a n
1aa6.pdb 546 KFDTPNGLAQFF----------------TCDWVAPIDKLT-----DEYPMVLSTVREVGH 584
1cxsa.pdb 580 PLGTPSGLIEI-YSKNIEKMGYDDCPAHPTWMEPA-ERLGG-AG-AKYPLHVVASHPKSR 635
1dmr.pdb 590 PLGTPTGLIEI-YSKNIEKMGYDDCPAHPTWMEPL-ERLDG-PG-AKYPLHIAASHPFNR 645
1tmo.pdb 594 PLGTPSGLIEI-FSRKIDQFGYDDCKGHPTWMEKT-ERSHGGPGSDKHPIWLQSCHPDKR 651
plgTP GLiei ptwme erl kyP hp r
1aa6.pdb 585 YSCRSMTGNC-AALAALAD--EPGYAQINTEDAKRLGIEDEALVWVHSRKGKIITRAQVS 641
1cxsa.pdb 636 LH-S-QLNGT-SLRDLYA-VAGHEPCLINPADAAARGIADGDVLRVFNDRGQILVGAKVS 691
1dmr.pdb 646 LH-S-QLNGT-VLREGYA-VQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVT 701
1tmo.pdb 652 LH-S-QMCESREYRETYA-VNGREPVYISPVDAKARGIKDGDIVRVFNDRGQLLAGAVVS 708
lh s q r yA g ep i p DA arGI Dgd vrV ndrGqil ga Vs
1aa6.pdb 642 DRPNKGAIYMTYQWW--------------------------------------------- 656
1cxsa.pdb 692 DAVMPGAIQIYEGGWYDPLD-------PSEE----GTLDKYG--DVNVLSLDVGTSKLAQ 738
1dmr.pdb 702 DAVMKGVIQIYEGGWYDPSD-------VTEP----GTLDKYG--DVNVLSADIGTSKLAQ 748
1tmo.pdb 709 DNFPKGIVRIHEGAWYGPVGKDGSTEGGAEVGALCSYGDPNTLT---LDIGTSK---LAQ 762
D kG i i eg W
1aa6.pdb 657 -PEYKYC-AVRVEPIAD-QR----A-AEQYVIDEYNKLKTRLREAALA------- 696
1cxsa.pdb 739 -GNCGQTILADVEKYAG-APVTVTVFDT--------------------PKGA--- 768
1dmr.pdb 749 -GNCGQTVLAEVEKYTG-PAVTLTGFVA--------------------PKAA--E 779
1tmo.pdb 763 ACSAYTC-LVEFEKYQGKVPKVSSF-DG--------------------PIEVEI- 794
l vEky g
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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