################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 11:35:44 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/p450.html ################################################################################################ #==================================== # Aligned_structures: 5 # 1: 1cpt.pdb # 2: 1oxa.pdb # 3: 1rom.pdb # 4: 2cpp.pdb # 5: 2hpda.pdb # # Length: 534 # Identity: 15/534 ( 2.8%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 47/534 ( 8.8%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 184/534 ( 34.5%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1cpt.pdb 1 M-----DA----RATIPEH---I-ARTV-----ILP-QGY----A-DDEVI-YPAFKWLR 35 1oxa.pdb 1 ------------------------A---TVPDLE-S-DSF-----HV--DW-YSTYAELR 23 1rom.pdb 1 -----------------------------APSFP-F-S--RASGPEP---P--AEFAKLR 22 2cpp.pdb 1 -NLAPLPP----HVPE--H---L-V---FDFDMY-NPSNL----SA---GV-QEAWAVLQ 37 2hpda.pdb 1 --------TIKEMPQPKTFGELKNLPLL-----NTD-------------KPVQALMKIAD 34 l 1cpt.pdb 36 D--EQPLAMAHIEGYDPMWIATKHADVMQIGKQPGLFSNAE--------GSEILYDQNNE 85 1oxa.pdb 24 E--TAPVTPVRFL-GQDAWLVTGYDEAKAALSDLRL-SSDPKKKYPGVEV--E-F-PAYL 75 1rom.pdb 23 A--TNPVSQVKLFDGSLAWLVTKHKDVCFVATSEKL-SKVRTR---QGFP--ELS-ASGK 73 2cpp.pdb 38 ESNVPDLVWTRCN--GGHWIATRGQLIREAYEDYRHFSSEC--------P--FIP-REAG 84 2hpda.pdb 35 E--LGEIFKFEAPG-RVTRYLSSQRLIKEACDE-SRFDKN--------------L-SQAL 75 w t s 1cpt.pdb 86 AFMRSISGGCPHVI--DSLTSMD-P-PTHTAYRGLTLNWFQPASIRKLEENIRRIAQASV 141 1oxa.pdb 76 GFPED-V----RNYFATNMGTSD-P-PTHTRLRKLVSQEFTVRRVEAMRPRVEQITAELL 128 1rom.pdb 74 QA----A----KAK--PTFVDMD-P-PEHMHQRSMVEPTFTPEAVKNLQPYIQRTVDDLL 121 2cpp.pdb 85 EA----Y------D--FIPTSMD-P-PEQRQFRALANQVVGMPVVDKLENRIQELACSLI 130 2hpda.pdb 76 KFVRDFA------G--DGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLV 127 d p p r f l 1cpt.pdb 142 QRLLDFD-G--ECDFM-TDCALYYPLHVVMTALG-VPEDDE-------PLMLKLTQD-FF 188 1oxa.pdb 129 DEVG-DS-G--VVDIV-DRFAHPLPIKVICELLG-VDEAAR-------GAFGRWSSEILV 175 1rom.pdb 122 EQMKQKGCANGPVDLV-KEFALPVPSYIIYTLLG-VPFNDL-------EYLTQQNAIRTN 172 2cpp.pdb 131 ESLR-PQ-G--QCNFT-EDYAEPFPIRIFMLLAG-LPEEDI-------PHLKYLTDQMTR 177 2hpda.pdb 128 QKWERLN-A--DEHIEVPEDMTRLTLDTIGLCGFNYRFN--SFYRDQPHPFITSMVRALD 182 a p g 1cpt.pdb 189 ---------------GV-E-AARRFHETIATFYDYFNGFTVDRRSCPKD--DVMSLLANS 229 1oxa.pdb 176 M---------------DPE-RAEQRGQAAREVVNFILDLVERRRTEPGD--DLLSALISV 217 1rom.pdb 173 ----------------G-SSTAREASAANQELLDYLAILVEQRLVEPKD--DIISKLCTE 213 2cpp.pdb 178 P---------------DGS-M-TF-AEAKEALYDYLIPIIEQRRQKPGT--DAISIVANG 217 2hpda.pdb 183 EAMNKLQRANPDDPAYD-E-NKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNG 240 d R p D s 1cpt.pdb 230 KLD--G---NYIDDKYINAYYVAIATAGHDTTSSSSGGAIIGLSRNPEQLALAKSDP--- 281 1oxa.pdb 218 QDDD-D---GRLSADELTSIALVLLLAGFEASVSLIGIGTYLLLTHPDQLALVRADP--- 270 1rom.pdb 214 Q-----VKPGNIDKSDAVQIAFLLLVAGNATMVNMIALGVATLAQHPDQLAQLKANP--- 265 2cpp.pdb 218 QVN--G---RPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERP--- 269 2hpda.pdb 241 KDPETG---EPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEE-AAR 296 l aG t L P l 1cpt.pdb 282 --------------A-LIPRLVDEAVRWTAPVKSF-MRTALADTEVR-GQNIKRGDRIML 324 1oxa.pdb 271 --------------S-ALPNAVEEILRYIAPPETT-TRFAAEEVEIG-GVAIPQYSTVLV 313 1rom.pdb 266 --------------S-LAPQFVEELCRYHTASALAIKRTAKEDVMIG-DKLVRANEGIIA 309 2cpp.pdb 270 --------------E-RIPAACEELLRRFSLV-AD-GRILTSDYEFH-GVQLKKGDQILL 311 2hpda.pdb 297 VLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAF-SLYAKEDTVLGGEYPLEKGDELMV 355 p E R r a d 1cpt.pdb 325 SYPSANRDEEVFS-NPDEFDITR-----F--P--NRHLGFGWGAHMCLGQHLAKLEMKIF 374 1oxa.pdb 314 ANGAANRDPSQFP-DPHRFDVTR-----D--T--RGHLSFGQGIHFCMGRPLAKLEGEVA 363 1rom.pdb 310 SNQSANRDEEVFE-NPDEFNMNR-----K--WPPQDPLGFGFGDHRCIAEHLAKAELTTV 361 2cpp.pdb 312 PQMLSGLDERENA-CPMHVDFSR-----Q--K--VSHTTFGHGSHLCLGQHLARREIIVT 361 2hpda.pdb 356 LIPQLHRDKTIWGDDVEEFRPERFENPSAIPQ--HAFKPFGNGQRACIGQQFALHEATLV 413 rD p f R FG G h C g lA E 1cpt.pdb 375 FEELLPKLKSVELSGP---PRL-VATNFVGGPKNVPIRFTK--A---------- 412 1oxa.pdb 364 LRALFGRFPALSLGIDADDVVWRRS-LLLRGIDHLPVRLD-------------G 403 1rom.pdb 362 FSTLYQKFPDLKVAVPLGKINYTPL-NRDVGIVDLPVIF--------------- 399 2cpp.pdb 362 LKEWLTRIPDFSIAPGA-QIQH-KS-GIVSGVQALPLVWDP--A----TTKAV- 405 2hpda.pdb 414 LGMMLKHFDF-EDHTNY-ELDI-KE-TLTLKPEGFVVKAKSKKIPLGG------ 457 g p #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################