################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 03:44:57 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/phs.html ################################################################################################ #==================================== # Aligned_structures: 3 # 1: 1ahpa.pdb # 2: 1gpb.pdb # 3: 1ygpa.pdb # # Length: 924 # Identity: 254/924 ( 27.5%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 529/924 ( 57.3%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 173/924 ( 18.7%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1ahpa.pdb 1 -----------------------------------SQPIF----NDKQFQEALSRQWQRY 21 1gpb.pdb 1 ----------------------------------------AGVENVTELKKNFNRHLHFT 20 1ygpa.pdb 1 TRRLTGFLPQEIKSIDTMIPLLSRALWNKHQVKKF----N----KAEDFQDRFIDHVETT 52 n fq f rh t 1ahpa.pdb 22 -GLNSAAEMTPRQWWLAVSEALAEMLRAQ---PFAKPV------ANQRHVNYISMEFLIG 71 1gpb.pdb 21 LVKDR-NVATPRDYYFALAHTVRDHLVGRWIRT-----QQHYYEKDPKRIYYLSLEFYMG 74 1ygpa.pdb 53 LARSL-YNCDDMVAYEAASMSIRDNLVIDWNKT-----QQKFTTRDPKRVYYLSLEFLMG 106 tpr y A s rd Lv t dpkrvyYlSlEFlmG 1ahpa.pdb 72 RLTGNNLLNL--GWYQDVQDSLKAYDINLTDLLEEEIDPALGAGGLGRLAACFLDSMATV 129 1gpb.pdb 75 RTLQNTMVNL--ALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATL 132 1ygpa.pdb 107 RALDNALINMKI-PREMIKGALDELGFKLEDVLDQEPDAGLGNGGLGRLAACFVDSMATE 165 R l N l Nl al lg ledlle E DagLGnGGLGRLAACFlDSMAT 1ahpa.pdb 130 GQSATGYGLNYQYGLFRQSFVDGKQVEAPDDWHRSNYPWFRHNEALDVQVGIGGAV-TK- 187 1gpb.pdb 133 GLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTS 192 1ygpa.pdb 166 GIPAWGYGLRYEYGIFAQKIIDGYQVETPDYWLNSGNPWEIERNEVQIPVTFYGYV-DRP 224 G A GYGlrYeyGiF Qki dG QvE pDdWlrsgnPWe r e pV fyG V 1ahpa.pdb 188 ---D-GRWEPEFTITGQAWDLPVVGYRNGVAQPLRLWQATHAH-PFDL--------TKFN 234 1gpb.pdb 193 --QG-AKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDF---NLKDFNVGGYI- 245 1ygpa.pdb 225 TTLSASQWIGGERVLAVAYDFPVPGFKTSNVNNLRLWQARPTT-EFDL--------NKFN 275 W vla ayD PVpGyrn vvn lRLWqA kf 1ahpa.pdb 235 DGDFLRA--EQQGINAEKLTKVLYPNDNHTAG-----KKLRLMQQYFQCACSVADILRRH 287 1gpb.pdb 246 -------QAVLDRNLAENISRVLYPND-----NFFEGKELRLKQEYFVVAATLQDIIRRF 293 1ygpa.pdb 276 NGDYKNS--VAQQQRAESITAVLYPNDNFAQG-----KELRLKQQYFWCAASLHDILRRF 328 v q AE it VLYPND KeLRLkQqYF cAasl DIlRRf 1ahpa.pdb 288 HLA-G-------RELHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKT 339 1gpb.pdb 294 KSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKT 353 1ygpa.pdb 329 KKS-K-------RPWTEFPDQVAIQLNDTHPTLAIVELQRVLVDLEKLDWHEAWDIVTKT 380 k s r efpD vaIQLNDTHPtlAIpEL RVLvDle ldWd AW it KT 1ahpa.pdb 340 FAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVV 399 1gpb.pdb 354 CAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLV 413 1ygpa.pdb 381 FAYTNHTVMQEALEKWPRRLFGHLLPRHLEIIYDINWFFLEDVAKKFPKDVDLLSRISII 440 fAYTNHTvmpEALErWpv L LLPRHlqIIyeIN rFl Vak fPgDvd l r s v 1ahpa.pdb 400 HD----KQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQL-WPNKFHNVTNGITPR 454 1gpb.pdb 414 EEGA-VKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYEL-EPHKFQNKTNGITPR 471 1ygpa.pdb 441 EENSPERQIRMAFLAIVGSHKVNGVVELHSELIKTTIFKDFIKFYGPSKFVNVTNGITPR 500 ee kqi MA LcivGshaVNGVa lHSel kktiFkdf l P KF NvTNGITPR 1ahpa.pdb 455 RWIKQCNPALAALLDKSL-Q--KEWANDLDQLINLVKLADDAKFRDLYRVIKQANKVRLA 511 1gpb.pdb 472 RWLVLCNPGLAEIIAERI-G--EEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFA 528 1ygpa.pdb 501 RWLKQANPSLAKLISETLNDPTEEYLLDMAKLTQLEKYVEDKEFLKKWNQVKLNNKIRLV 560 RWlkqcNP LA li e l eEy DldqL L kyvdD F vKq NK rla 1ahpa.pdb 512 EFVKVRT-G---IDI--NPQAIFDIQIKRLHEYKRQHLNLLRILALYKEIRENP----Q- 560 1gpb.pdb 529 AYLEREY-K---VHI--NPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEP----N- 577 1ygpa.pdb 561 DLIKKENDGVDIINREYLDDTLFDMQVKRIHEYKRQQLNVFGIIYRYLAMKNMLKNGASI 620 k e g i i np lFD QvKRiHEYKRQ LN l ii lY ik p 1ahpa.pdb 561 --AD--RVPRVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVS 616 1gpb.pdb 578 --KF--VVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVS 633 1ygpa.pdb 621 EEVARKYPRKVSIFGGKSAPGYYMAKLIIKLINCVADIVNNDESIEHLLKVVFVADYNVS 680 vprv fGgKaAPGYymAK IIklIn vaDvvNnDp vgd LkVvFl dY VS 1ahpa.pdb 617 AAEKLIPAADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIF 676 1gpb.pdb 634 LAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIF 693 1ygpa.pdb 681 KAEIIIPASDLSEHISTAGTEASGTSNMKFVMNGGLIIGTVDGANVEITREIGEDNVFLF 740 AEk IPAaDlSEqISTAGtEASGTgNMKf lNGaLtiGT DGANVEiaee GEeN FiF 1ahpa.pdb 677 GHTVKQVKAILAKG------YDPVKWRKKDKVLDAVLKELE-SGKYSDGDKHAFDQMLHS 729 1gpb.pdb 694 GMRVEDVDRLDQRG------YNAQEYYDRIPELRQIIEQLS-SGFFSPKQPDLFKDIVNM 746 1ygpa.pdb 741 GNLSENVEELRYNHQYHPQD--------LPSSLDSVLSYIEQ---FSPENPNEFKPLVDS 789 G ve V l g Ld vl le fSp p Fk v s 1ahpa.pdb 730 IGKQGGDPYLVMADFAAYVEAQKQVDVLY-RDQEAWTRAAILNTARCGMFSSDRSIRDYQ 788 1gpb.pdb 747 LMH--HDRFKVFADYEEYVKCQERVSALY-KNPREWTRMVIRNIATSGKFSSDRTIAQYA 803 1ygpa.pdb 790 IK-YHGDYYLVSDDFESYLATHELVDQEFHNQRSEWLKKSVLSLANVGFFSSDRCIEEYS 848 i gD ylV aDfe Yv qe Vd ly eWtr iln A G FSSDR I Y 1ahpa.pdb 789 ARIWQAAR---------------- 796 1gpb.pdb 804 REIWG---VEPS-RQRLPAPDEKI 823 1ygpa.pdb 849 DTIWN---VEPVT----------- 858 IW #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################